Cart
sales@molnova.com
VPS34 inhibitor 1 (Compound 19 PIK-III analogue)
CAS No. 1383716-46-8
VPS34 inhibitor 1 (Compound 19 PIK-III analogue) ( PIK-III analogue )
Catalog No. M21136 CAS No. 1383716-46-8
VPS34 inhibitor 1 (Compound 19 PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 111 | Get Quote |
|
| 5MG | 201 | Get Quote |
|
| 10MG | 309 | Get Quote |
|
| 25MG | 521 | Get Quote |
|
| 50MG | 746 | Get Quote |
|
| 100MG | 1035 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameVPS34 inhibitor 1 (Compound 19 PIK-III analogue)
-
NoteResearch use only not for human use.
-
Brief DescriptionVPS34 inhibitor 1 (Compound 19 PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM).
-
DescriptionVPS34 inhibitor 1 (Compound 19 PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM).
-
SynonymsPIK-III analogue
-
PathwayPI3K/Akt/mTOR signaling
-
TargetPI3K
-
RecptorVps34
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1383716-46-8
-
Formula Weight391.47
-
Molecular FormulaC21H25N7O
-
Purity>98% (HPLC)
-
SolubilityDMSO:78 mg/mL (199.25 mM)
-
SMILESCC(C)(O)CNc1ncc(-c2ccnc(Nc3ccncc3)n2)c(CC2CC2)n1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Honda A Harrington E Cornella-Taracido I et al. Potent Selective and Orally Bioavailable Inhibitors of VPS34 Provide Chemical Tools to Modulate Autophagy in Vivo[J]. ACS Medicinal Chemistry Letters 2015 7(1).
molnova catalog
related products
-
GDC-0326
A potent, selective, orally available PI3Kα inhibitor with Ki of 0.2 nM; displays 133, 20 and 33-fold selectivity over PI3Kβ, PI3Kδ and PI3Kγ, respectively.
-
ON 146040
ON 146040 is an effective inhibitor of PI3K isoforms with IC50s of 14 and 20 nM for PI3Kα and PI3Kδ, respectively.
-
TGX-221
A potent, selective PI3K p110β inhibitor with IC50 of 8.5 nM.
